Molecular and Genomic Approaches for Improving Risk in Breast Cancer
Amy Degnim, M.D.. Mayo Clinic, Department of Surgery
April 2015 - June 2017
Breast cancer study at Mayo clinic. Our contribution focuses on applying analytical approaches to discover relevant genes that are predictors of cancer development. DNA from thousands of tissue samples from biopsies performed at Mayo over the last 40 years. These biopsies were benign, yet some develop into cancer in later years. Our work focuses on two categories that sometimes develop into cancers (Sclerosing Adenosis, Atypical Hyperplasias).
Success in this project results in a better predictive marker of breast cancer development that can be used in the clinical lab and informs clinical care, resulting in lives saved and targeted treatments.