Working closely with NCSA’s Healthcare Innovation Program Office, the Visual Analytics group is part of an ongoing collaboration with researchers at the NIH National Institute of Allergy and Infectious Disease, Institute for Systems Biology and Illinois Department of Statistics. This interdisciplinary team is taking an “all-inclusive” approach in studying the disease pathogenesis of influenzae and, more recently, COVID-19. Their goal is to understand the beginning-to-end biological responses to viral attack from the standpoint of multiple key players, including the invading virus, defending host cell, and overall system (e.g., human body). With comprehensive studies come vast amounts of data, and not all data that is statistically significant is biologically relevant. The team works together to pull out the pertinent information from the data and present them in a clear and simple way. Equipped with experts from biology and computer science and a certain curiosity in one another’s disciplines, the team aptly integrates the appropriate scientific contexts into advanced statistical and machine learning methods in order to accurately interpret time series data from ongoing clinical studies. The team’s publications thus far have provided insight on why and how viruses and immune cells behave, interact with each other and lead to the manifestation of clinical symptoms. Ultimately, they hope their findings will help identify actionable targets for new therapies for influenzae and COVID-19.